Phosphatidylserine is a chemical. The body can make phosphatidylserine, but gets most of what it needs from foods. Phosphatidylserine supplements were once made from cow brains, but now are commonly manufactured from cabbage or soy. It is vital for cognitive function, but is not necessarily needed as the body synthesizes it. However, Phosphatidylserine (PS) supplementation in older individuals seems to improve memory and cognitive capacity.
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Active ingredient: |
Phosphatidylserine(PS) |
Molecular formula: |
C13H24NO10P |
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Molecule weight： |
385.3041 |
CAS number: |
51446-62-9 |
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Molecule structure： |
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PS is a naturally occurring phospholipid or "good fat" that is found in cell membranes and is essential to the functioning of all cells in the body. It is, however, particularly abundant in brain cells where it functions as a brain cell regulator with regard to neurotransmission and synaptic communication. Both neurotransmission and synaptic communication are key elements in maintaining memory, the ability to learn and sustained concentration.
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ANALYSIS |
SPECIFICATION |
RESULTS |
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L-α-Phosphatidyl-L-serine |
≥20.0% |
21.2% HPLC |
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L-α-Phosphatidylcholine |
≤10.0% |
10.31% HPLC |
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L-α-Phosphatidylethanolamine |
≤10.0% |
7.16% HPLC |
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L-α-Phosphatidylinositol |
≤5.0% |
1.12% HPLC |
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L-α-Phoshatidic acid |
≤15.0% |
12.64% HPLC |
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Organoleptic |
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Appearance |
Fine Powder |
Conform |
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Color |
Light Yellow or Brown Powder |
Conform |
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Odor |
Characteristic |
Conform |
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Taste |
Characteristic |
Conform |
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Physical Characteristics |
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Solubility |
Soluble in chloroform, n-hexane, diethyl ether, Petroleum ether; Insoluble in water, ethanol, methanol. |
Conform |
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Peroxide value |
≤10meq/kg |
Conform |
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Particle Size (80 mesh) |
≥98.0% pass 80 mesh |
Conform |
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Loss on drying |
≤2.0% |
0.75% |
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Ash Content |
≤1.0% |
0.34% |
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Solvent Residue |
Eur Pharm |
Conform |
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Heavy metals |
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Total Heavy Metals |
≤10.0ppm |
Conform |
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As |
≤2.0ppm |
Conform |
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Lead |
≤2.0ppm |
Conform |
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Cadmium(Cd) |
≤2.0 ppm |
Conform |
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Mercury |
≤0.5 ppm |
Conform |
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ANALYSIS |
SPECIFICATION |
RESULTS |
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L-α-Phosphatidyl-L-serine |
≥50.0% |
53.10% HPLC |
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L-α-Phosphatidylcholine |
≤10.0% |
9.01% HPLC |
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L-α-Phosphatidylethanolamine |
≤10.0% |
7.85% HPLC |
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L-α-Phosphatidylinositol |
≤5.0% |
1.21% HPLC |
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L-α-Phoshatidic acid |
≤15.0% |
10.31% HPLC |
|
Organoleptic |
||
|
Appearance |
Fine Powder |
Conform |
|
Color |
Light Yellow or Brown Powder |
Conform |
|
Odor |
Characteristic |
Conform |
|
Taste |
Characteristic |
Conform |
|
Physical Characteristics |
||
|
Solubility |
Soluble in chloroform, n-hexane, diethyl ether, Petroleum ether; Insoluble in water, ethanol, methanol. |
Conform |
|
Peroxide value |
≤10meq/kg |
Conform |
|
Particle Size (80 mesh) |
≥98.0% pass 80 mesh |
Conform |
|
Loss on drying |
≤2.0% |
0.91% |
|
Ash Content |
≤1.0% |
0.54% |
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Solvent Residue |
Eur Pharm |
Conform |
|
Heavy metals |
||
|
Total Heavy Metals |
≤10.0ppm |
Conform |
|
As |
≤2.0ppm |
Conform |
|
Lead |
≤2.0ppm |
Conform |
|
Cadmium(Cd) |
≤2.0 ppm |
Conform |
|
Mercury |
≤0.5 ppm |
Conform |
1. Age-Related Cognitive Decline (Alzheimer's disease)
Studies have shown taking Phosphatidylserine improve attention, language skills, and memory in aging people with declining thinking skills. Phosphatidylserine supplementation has also been shown to improve mental function, such as the ability to remember names and to recall the location of frequently misplaced objects, in people with less severe Alzheimer’s disease. Phosphatidylserine plays an essential role in cell membrane composition and cell-to-cell communication, especially in the brain. It may enhance healthy memory and thinking ability by assisting in the conduction of electrical impulses and facilitating the activity of neurotransmitters involved in learning and memory.
Recommended dosage —— 100 mg of phosphatidylserine three times daily
2. Attention Deficit Hyperactivity Disorder (ADHD)
There appears to be improved attention and reduced symptoms of hyperactivity in children given Phosphatidylserine, which may promote attention to an even greater degree when the PS is complexed with fish oils
Recommended dosage —— 200mg of phosphatidylserine daily
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